Effect of astragalus polysaccharides on cancer cells studied by AFM
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AbstractAs a traditional Chinese medicine, astragalus and its products are used in cancer treatment aiming to reduce the side effects of chemotherapy. Cells are the most basic unit of living organisms, and AFM directly obtains information from living cells on the micro/nano scale. Therefore, the use of AFM to study the interaction between astragalus and cells is conducive to a full range of drug efficacy evaluation and provides a new way for drug development. In this paper, astragalus polysaccharides were extracted from astragalus, which were diluted into solutions of different concentrations. Combined with the MTT experiment, the effects of Astragalus polysaccharide on cancer cells and benign cells were studied by AFM.
CitationLu Z, Wang Z, Li D, Zhu W, Wang R, Qu K, Yan J (2021) 'Effect of astragalus polysaccharides on cancer cells studied by AFM', 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO) - Xi'an, China, IEEE.
TypeConference papers, meetings and proceedings
SponsorsThis work was supported by National Key R&D Program of China (No. 2017YFE0112100), EU H2020 Program (MNR4SCell No.734174), National Natural Science Foundation Program of China (No. 62175020), Jilin Provincial Science and Technology Program (Nos. 2020C022-1, 20190201287JC, 20190702002GH and 20200901011SF), Jilin Province Education Department Program (No. JJKH20210833KJ), and “111” Project of China (No. D17017).
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