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dc.contributor.authorWang, Bowei
dc.contributor.authorYang, Fan
dc.contributor.authorDong, Jianjun
dc.contributor.authorLi, Jiani
dc.contributor.authorWang, Ying
dc.contributor.authorQu, Kaige
dc.contributor.authorWei, Huimiao
dc.contributor.authorWang, Zuobin
dc.date.accessioned2022-03-17T10:42:34Z
dc.date.available2022-03-17T00:00:00Z
dc.date.available2022-03-17T10:42:34Z
dc.date.issued2021-11-18
dc.identifier.citationWang B, Yang F, Dong J, Li J, Wang Y, Qu K, Wei H, Wang Z (2021) 'Analysis of the mechanical properties of chromosomes in air and liquid by AFM', 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO) - Xi'an, China, .en_US
dc.identifier.isbn9781665448826
dc.identifier.doi10.1109/3M-NANO49087.2021.9599772
dc.identifier.urihttp://hdl.handle.net/10547/625349
dc.description.abstractChromosomes contain all the genomic information thus making the study of chromosomes practical and significant. Herein, the morphologies of chromosomes prepared with different methods were monitored by atomic force microscopy (AFM). Moreover, the mechanical properties of chromosomes in air and liquid were investigated quantitatively through AFM-based force spectroscopy. The differences of chromosome morphologies and mechanical properties caused by sample preparations indicated that the chromosome characterization in liquid was more meaningful to reveal the physiological characteristics of chromosomes.en_US
dc.description.sponsorshipThis work was supported by National Key R&D Program of China (No. 2017YFE0112100), EU H2020 Program MNR4SCell No. 734174; NanoStencil No. 767285), Jilin Provincial Science and Technology Program (Nos. 2020C022-1, 20190201287JC, 20190702002GH and 20200901011SF), Jilin Province Education Department Program (Nos. JJKH20210833KJ), and “111” Project of China (No. D17017).en_US
dc.language.isoenen_US
dc.publisherIEEEen_US
dc.relation.urlhttps://ieeexplore.ieee.org/document/9599772en_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectatomic force microscopyen_US
dc.subjectchromosomeen_US
dc.subjectmorphologyen_US
dc.subjectmechanical propertiesen_US
dc.subjectSubject Categories::J990 Technologies not elsewhere classifieden_US
dc.titleAnalysis of the mechanical properties of chromosomes in air and liquid by AFMen_US
dc.typeConference papers, meetings and proceedingsen_US
dc.contributor.departmentChangchun University of Science and Technologyen_US
dc.contributor.departmentChangli Nano Biotechnology Ltden_US
dc.contributor.departmentUniversity of Bedfordshireen_US
dc.date.updated2022-03-17T10:38:00Z
dc.description.noteDate of Acceptance: 1/7/2021 see http://conferences.ieeeauthorcenter.ieee.org/wp-content/uploads/sites/8/IEEE-Conference-Paper-Sharing-and-Posting-Policies.pdf authors are permitted to upload accepted version to repositories


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