Analysis of the mechanical properties of chromosomes in air and liquid by AFM
Name:
13-AnalysisoftheMechanicalProp ...
Size:
489.1Kb
Format:
PDF
Description:
author's accepted version
Affiliation
Changchun University of Science and TechnologyChangli Nano Biotechnology Ltd
University of Bedfordshire
Issue Date
2021-11-18Subjects
atomic force microscopychromosome
morphology
mechanical properties
Subject Categories::J990 Technologies not elsewhere classified
Metadata
Show full item recordAbstract
Chromosomes contain all the genomic information thus making the study of chromosomes practical and significant. Herein, the morphologies of chromosomes prepared with different methods were monitored by atomic force microscopy (AFM). Moreover, the mechanical properties of chromosomes in air and liquid were investigated quantitatively through AFM-based force spectroscopy. The differences of chromosome morphologies and mechanical properties caused by sample preparations indicated that the chromosome characterization in liquid was more meaningful to reveal the physiological characteristics of chromosomes.Citation
Wang B, Yang F, Dong J, Li J, Wang Y, Qu K, Wei H, Wang Z (2021) 'Analysis of the mechanical properties of chromosomes in air and liquid by AFM', 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO) - Xi'an, China, .Publisher
IEEEAdditional Links
https://ieeexplore.ieee.org/document/9599772Type
Conference papers, meetings and proceedingsLanguage
enISBN
9781665448826Sponsors
This work was supported by National Key R&D Program of China (No. 2017YFE0112100), EU H2020 Program MNR4SCell No. 734174; NanoStencil No. 767285), Jilin Provincial Science and Technology Program (Nos. 2020C022-1, 20190201287JC, 20190702002GH and 20200901011SF), Jilin Province Education Department Program (Nos. JJKH20210833KJ), and “111” Project of China (No. D17017).ae974a485f413a2113503eed53cd6c53
10.1109/3M-NANO49087.2021.9599772
Scopus Count
Collections
The following license files are associated with this item:
- Creative Commons
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 International