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17-Multi-parameterAFMCharacter ...
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Issue Date
2021-11-18Subjects
multi-parameter AFMforce curves
cell mechanics
INS-1 cells
Subject Categories::C131 Applied Cell Biology
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AFM-based single cell force spectroscopy has been employed wildly, while more work is needed for the mechanical detection of diabetes-related cells (INS-1 cells). In this study, a multi-parameter AFM characterization was performed to detect the mechanical properties of INS-1 cells in situ. High resolution topographies and concurrent mechanics were obtained by taking the advantage of the quantitatively imaging (QI) mode AFM. The analyses of force curves and force maps jointly presented the multiple parameters involved in the cell mechanics. The AFM force spectroscopy measurement provides full analysis and comprehensive understanding of cell mechanics.Citation
Yang F, Wang B, Wang J, Chen Y, Wang Z (2021) 'Multi-parameter AFM characterization of INS-1 cells', 2021 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO) - Xi'an, China, IEEE.Publisher
IEEEAdditional Links
https://ieeexplore.ieee.org/document/9599761Type
Conference papers, meetings and proceedingsLanguage
enISBN
9781665448826Sponsors
This work was supported by National Key R&D Program of China (No. 2017YFE0112100), EU H2020 Program (MNR4SCell No.734174; NanoStencil No. 767285), Jilin Provincial Science and Technology Program (Nos. 2020C022-1, 20190201287JC, 20190702002GH and 20200901011SF), Jilin Province Education Department Program (No. JJKH20210833KJ), and “111” Project of China (No. D17017). This work was also supported by Chinese Scholarship Council grant (No. 202007585007).ae974a485f413a2113503eed53cd6c53
10.1109/3M-NANO49087.2021.9599761
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