Growth of nerve cells induced by diverse nanopillar arrays

Abstract

The nanotopographies can induce the growth of nerve cells and the growth of their synapses. Studying the anisotropic structures for the guidance of neuronal synapses is beneficial to the in vitro repair of neurons and the development of regenerative medicine. Thus, studying how diverse nanopillar arrays affect the growth of nerve cells is essential. This paper employed the technology of laser interference lithography (LIL) to fabricate different nanopillar arrays with the same and different size gaps between the X and Y directions, and observe how the structures induce the growth of nerve cells and their synapses.