Acute effects of breaking up prolonged sedentary time on cardiovascular disease risk markers in adults with paraplegia
Authors
Bailey, Daniel PaulWithers, Thomas M.
Goosey-Tolfrey, Victoria L.
Dunstan, David W.
Leicht, Christof A.
Champion, Rachael B.
Charlett, Opie P.
Ferrandino, Louise
Issue Date
2020-04-03Subjects
physical activitysedentary behaviour
cardiometabolic risk
exercise
spinal cord injuries
well-being
Subject Categories::C600 Sports Science
Metadata
Show full item recordAbstract
Elevated levels of cardiovascular disease (CVD) risk markers are highly prevalent in people with a spinal cord injury (SCI). Breaking up prolonged sedentary time with short, regular bouts of physical activity can reduce postprandial glucose and lipid levels in able-bodied individuals. The effects in people with paraplegia are unknown. The study aims were to examine the acute postprandial glucose (primary aim), lipid, blood pressure, and psychological responses (secondary aims) to breaking up prolonged sedentary time in individuals with paraplegia. This was a randomized crossover design trial. Fourteen participants with paraplegia (age 51 +- 9 years, trunk fat mass 44.3 +- 7.7%) took part in the following two, 5.5-hour conditions: (1) uninterrupted sedentary time (SED), and (2) sedentary time interrupted with 2 minutes of moderate-intensity arm crank ergometer physical activity every 20 minutes (SEDACT). Standardized breakfast and lunch test meals were consumed during each condition. The outcomes were compared between conditions using linear mixed models. Glucose area under the curve (AUC) was significantly lower during the lunch postprandial period in SED-ACT vs SED (incremental AUC 1.9 [95% CI 1.0, 2.7) and 3.0 [2.1, 3.9] mmol/L∙2.5 hour, respectively, P = .015, f = 0.34). There were no differences between conditions for the breakfast or total 5.5 hours postprandial periods (P > .05). Positive affect was higher in SED-ACT than SED (P = .001). Breaking up prolonged sedentary time acutely attenuates lunch postprandial glucose and improves positive affect in people with paraplegia. This may have clinical relevance for reducing CVD risk and improving psychological well-being in this population.Citation
Bailey D, Withers T, Goosey-Tolfrey V, Dunstan D, Leicht C, Champion R, Charlotte O, Ferrandino L. (2020) 'Acute effects of breaking up prolonged sedentary time on cardiovascular disease risk markers in adults with paraplegia', Scandinavian Journal of Medicine and Science in Sports, 30 (8), pp.1398-1408.Publisher
John Wiley and SonsPubMed ID
32243644Additional Links
https://onlinelibrary.wiley.com/doi/full/10.1111/sms.13671Type
ArticleLanguage
enISSN
0905-7188ae974a485f413a2113503eed53cd6c53
10.1111/sms.13671
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