Acute effects of breaking up prolonged sedentary time on cardiovascular disease risk markers in adults with paraplegia
AuthorsBailey, Daniel Paul
Withers, Thomas M.
Goosey-Tolfrey, Victoria L.
Dunstan, David W.
Leicht, Christof A.
Champion, Rachael B.
Charlett, Opie P.
spinal cord injuries
Subject Categories::C600 Sports Science
MetadataShow full item record
AbstractElevated levels of cardiovascular disease (CVD) risk markers are highly prevalent in people with a spinal cord injury (SCI). Breaking up prolonged sedentary time with short, regular bouts of physical activity can reduce postprandial glucose and lipid levels in able-bodied individuals. The effects in people with paraplegia are unknown. The study aims were to examine the acute postprandial glucose (primary aim), lipid, blood pressure, and psychological responses (secondary aims) to breaking up prolonged sedentary time in individuals with paraplegia. This was a randomized crossover design trial. Fourteen participants with paraplegia (age 51 +- 9 years, trunk fat mass 44.3 +- 7.7%) took part in the following two, 5.5-hour conditions: (1) uninterrupted sedentary time (SED), and (2) sedentary time interrupted with 2 minutes of moderate-intensity arm crank ergometer physical activity every 20 minutes (SEDACT). Standardized breakfast and lunch test meals were consumed during each condition. The outcomes were compared between conditions using linear mixed models. Glucose area under the curve (AUC) was significantly lower during the lunch postprandial period in SED-ACT vs SED (incremental AUC 1.9 [95% CI 1.0, 2.7) and 3.0 [2.1, 3.9] mmol/L∙2.5 hour, respectively, P = .015, f = 0.34). There were no differences between conditions for the breakfast or total 5.5 hours postprandial periods (P > .05). Positive affect was higher in SED-ACT than SED (P = .001). Breaking up prolonged sedentary time acutely attenuates lunch postprandial glucose and improves positive affect in people with paraplegia. This may have clinical relevance for reducing CVD risk and improving psychological well-being in this population.
CitationBailey D, Withers T, Goosey-Tolfrey V, Dunstan D, Leicht C, Champion R, Charlotte O, Ferrandino L. (2020) 'Acute effects of breaking up prolonged sedentary time on cardiovascular disease risk markers in adults with paraplegia', Scandinavian Journal of Medicine and Science in Sports, 30 (8), pp.1398-1408.
PublisherJohn Wiley and Sons
The following license files are associated with this item:
- Creative Commons
Except where otherwise noted, this item's license is described as Yellow - can archive pre-print (ie pre-refereeing)
- Cardiovascular disease risk marker responses to breaking up prolonged sedentary time in individuals with paraplegia: the Spinal Cord Injury Move More (SCIMM) randomised crossover laboratory trial protocol.
- Authors: Withers TM, Croft L, Goosey-Tolfrey VL, Dunstan DW, Leicht CA, Bailey DP
- Issue date: 2018 Jun 22
- Cardiometabolic Response to a Single High-intensity Interval Exercise Session Versus Breaking up Sedentary Time with Fragmented High-intensity Interval Exercise.
- Authors: Bailey DP, Orton CJ, Maylor BD, Zakrzewski-Fruer JK
- Issue date: 2019 Mar
- Effects of breaking up prolonged sitting following low and high glycaemic index breakfast consumption on glucose and insulin concentrations.
- Authors: Bailey DP, Maylor BD, Orton CJ, Zakrzewski-Fruer JK
- Issue date: 2017 Jul
- Impaired postprandial glucose and no improvement in other cardiometabolic responses or cognitive function by breaking up sitting with bodyweight resistance exercises: a randomised crossover trial.
- Authors: Charlett OP, Morari V, Bailey DP
- Issue date: 2021 Apr
- Multiple Short Bouts of Walking Activity Attenuate Glucose Response in Obese Women.
- Authors: Rodriguez-Hernandez M, Martin JS, Pascoe DD, Roberts MD, Wadsworth DW
- Issue date: 2018 Apr 1