Risk models and scores for metabolic syndrome: systematic review protocol
Affiliation
University of BedfordshireIssue Date
2019-09-27Subjects
metabolic syndromeprediction
risk score
systematic review protocol
H123 Public Health Engineering
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Introduction Metabolic syndrome ‘a clustering of risk factors which includes hypertension central obesity, impaired glucose metabolism with insulin resistance and dyslipidaemia’ affects approximately 20%–25% of the global adult population. Individuals with metabolic syndrome have two to threefold risk of developing cardiovascular disease and a fivefold risk of developing developing diabetes and death from all causes. Although there is rapid proliferation of risk scores for predicting the risk of developing metabolic syndrome later in life, yet, these are seldom used in the practice. Therefore, the purpose of this review is to determine the performance of risk models and scores for predicting the metabolic syndrome. Methods and analysis Articles will be sought for from electronic databases (MEDLINE, CINAHL, PubMed and Web of Science) as well as the Cochrane Library. Further manual search of reference lists and grey literatures will be conducted. The search will cover from the start of indexing to 3 October 2018. Identified studies will be included if they fulfil the study selection criteria. Quality of studies will be appraised using suitable criteria for the risk models. The risk scores in the final sample of the review will be ranked/prioritised based on previous quality criteria for prognostic risk models. Lastly, the impact of the models will be ascertained by tracking citations on Google Scholar. Ethics and dissemination This study does not require formal ethical approval as primary data will not be collected. The results will be disseminated through a peer-reviewed publication and relevant conference presentations.Citation
Ibrahim MS, Pang D, Randhawa G, Pappas Y (2019) 'Risk models and scores for metabolic syndrome: systematic review protocol', BMJ Open, 9 (e027326)Publisher
BMJJournal
BMJ OpenPubMed ID
31562141PubMed Central ID
PMC6773348Additional Links
https://bmjopen.bmj.com/content/9/9/e027326https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773348/
Type
ArticleLanguage
enISSN
2044-6055ae974a485f413a2113503eed53cd6c53
10.1136/bmjopen-2018-027326
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- Creative Commons
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