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dc.contributor.authorHu, Jingen
dc.contributor.authorJiao, Jieen
dc.contributor.authorWang, Yingen
dc.contributor.authorGao, Mingyanen
dc.contributor.authorLu, Zhengchengen
dc.contributor.authorYang, Fanen
dc.contributor.authorHu, Cuihuaen
dc.contributor.authorSong, Zhengxunen
dc.contributor.authorChen, Yujuanen
dc.contributor.authorWang, Zuobinen
dc.date.accessioned2019-10-31T10:28:49Z
dc.date.available2019-10-31T10:28:49Z
dc.date.issued2019-07-02
dc.identifier.citationHu J, Jiao J, Wang Y, Gao M, Lu Z, Yang F, Hu C, Song Z, Chen Y, Wang Z (2019) 'Effect of extract from ginseng rust rot on the inhibition of human hepatocellular carcinoma cells in vitro', Micron, 124 (), pp.102710-.en
dc.identifier.issn0968-4328
dc.identifier.pmid31280008
dc.identifier.doi10.1016/j.micron.2019.102710
dc.identifier.urihttp://hdl.handle.net/10547/623556
dc.description.abstractHepatocellular carcinoma (HCC) is one of major leading causes of cancer death worldwide. As a traditional medicine, the anti-cancer function of ginseng is being growingly recognized and investigated. However, the effect of ginseng rust rot on human HCC is unknown yet. In this study, the HCC cells were treated with different parts of mountain cultivated ginseng rust rot and compared with human normal liver cells. The morphology, survival rate and β-actin expression of the cells were changed by introducing the ginseng epidermis during the incubation process. Notably, the results reveal that the ginseng epidermis can induce apoptosis by altering the morphologies of cells, indicating the practical implication for the HCC treatment and drug development.
dc.description.sponsorshipNational Key R&D Program of China (No.2017YFE0112100), EU H2020 Program (MNR4SCELL No.734174), Jilin Provincial Science and Technology Program (Nos. 20160623002TC, 20180414002GH, 20180414081GH, 20180520203JH and 20190702002GH), and “111” Project of China (D17017)en
dc.language.isoenen
dc.publisherELSEVIERen
dc.relation.urlhttps://www.sciencedirect.com/science/article/pii/S0968432819301337?via=ihuben
dc.rightsGreen - can archive pre-print and post-print or publisher's version/PDF
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectanti-tumour effecten
dc.subjectginseng-extracted compoundsen
dc.subjecthepatocelluar carcinomaen
dc.subjectC130 Cell Biologyen
dc.titleEffect of extract from ginseng rust rot on the inhibition of human hepatocellular carcinoma cells in vitroen
dc.typeArticleen
dc.contributor.departmentChangchun University of Science and Technologyen
dc.contributor.departmentUniversity of Bedfordshireen
dc.identifier.journalMicronen
dc.date.updated2019-10-31T09:58:43Z
html.description.abstractHepatocellular carcinoma (HCC) is one of major leading causes of cancer death worldwide. As a traditional medicine, the anti-cancer function of ginseng is being growingly recognized and investigated. However, the effect of ginseng rust rot on human HCC is unknown yet. In this study, the HCC cells were treated with different parts of mountain cultivated ginseng rust rot and compared with human normal liver cells. The morphology, survival rate and β-actin expression of the cells were changed by introducing the ginseng epidermis during the incubation process. Notably, the results reveal that the ginseng epidermis can induce apoptosis by altering the morphologies of cells, indicating the practical implication for the HCC treatment and drug development.


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