A pilot study to detect human circadian rhythms using a novel thoracic temperature sensor
Authors
Chkeir, AlyMourad-Chehade, Farah
Hewson, David
Duchêne, Jacques
Levi, Francis
Beau, Jacques
Maurice, Monique
Komarzynski, Sandra
Affiliation
University of Technology of TroyesUniversity of Bedfordshire
Warwick University
University of Paris
Issue Date
2016-12-31
Metadata
Show full item recordAbstract
Perturbations of circadian rhythms have been related to cancer progression and worsening of metabolic diseases. This paper aims at optimizing the analytical methods suited for the detection of such perturbations using skin temperature signals as a circadian biomarker. Five control subjects were evaluated in this pilot study. Skin temperature was recorded every five minutes for four days. Using a novel thoracic infrared sensor. Four different interpolation methods were compared in order to replace missing values and help subsequently prolong sensor battery life. A Cosinor model was used to characterize circadian rhythms, and compute relevant parameters, with their confidence limits. A divergence study is then proposed to detect changes in these parameters. The results support the enlargement of the sample size and warrant further assessment in cancer patients.Citation
Chkeir A, Mourad-Chehade F, Hewson DJ, Duchene J, Levi F, Beau J, Maurice M, Komarzynski S (2016) 'A pilot study to detect human circadian rhythms using a novel thoracic temperature sensor', 2016 International Conference on Bio-engineering for Smart Technologies (BioSMART) - Dubai, IEEE.Publisher
IEEEAdditional Links
https://ieeexplore.ieee.org/abstract/document/7835464Type
Conference papers, meetings and proceedingsLanguage
enae974a485f413a2113503eed53cd6c53
10.1109/BIOSMART.2016.7835464