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dc.contributor.authorBaroncelli, Riccardoen
dc.contributor.authorAmby, Daniel Buchvaldten
dc.contributor.authorZapparata, Antonioen
dc.contributor.authorSarrocco, Sabrinaen
dc.contributor.authorVannacci, Giovannien
dc.contributor.authorLe Floch, Gaétanen
dc.contributor.authorHarrison, Richarden
dc.contributor.authorHolub, Ericen
dc.contributor.authorSukno, Serenella A.en
dc.contributor.authorSreenivasaprasad, Surapareddyen
dc.contributor.authorThon, Michael R.en
dc.date.accessioned2019-01-28T11:22:46Z
dc.date.available2019-01-28T11:22:46Z
dc.date.issued2016-08-05
dc.identifier.citationBaroncelli R, Amby DB, Zapparata A, Sarrocco S, Vannacci G, Le Floch G, Harrison RJ, Holub E, Sukno SA, Sreenivasaprasad S, Thon MR (2016) 'Gene family expansions and contractions are associated with host range in plant pathogens of the genus Colletotrichum', BMC Genomics, 17 (), pp.555-.en
dc.identifier.issn1471-2164
dc.identifier.pmid27496087
dc.identifier.doi10.1186/s12864-016-2917-6
dc.identifier.urihttp://hdl.handle.net/10547/623096
dc.description.abstractMany species belonging to the genus Colletotrichum cause anthracnose disease on a wide range of plant species. In addition to their economic impact, the genus Colletotrichum is a useful model for the study of the evolution of host specificity, speciation and reproductive behaviors. Genome projects of Colletotrichum species have already opened a new era for studying the evolution of pathogenesis in fungi. We sequenced and annotated the genomes of four strains in the Colletotrichum acutatum species complex (CAsc), a clade of broad host range pathogens within the genus. The four CAsc proteomes and secretomes along with those representing an additional 13 species (six Colletotrichum spp. and seven other Sordariomycetes) were classified into protein families using a variety of tools. Hierarchical clustering of gene family and functional domain assignments, and phylogenetic analyses revealed lineage specific losses of carbohydrate-active enzymes (CAZymes) and proteases encoding genes in Colletotrichum species that have narrow host range as well as duplications of these families in the CAsc. We also found a lineage specific expansion of necrosis and ethylene-inducing peptide 1 (Nep1)-like protein (NLPs) families within the CAsc. This study illustrates the plasticity of Colletotrichum genomes, and shows that major changes in host range are associated with relatively recent changes in gene content.
dc.language.isoenen
dc.publisherBioMed Centralen
dc.relation.urlhttps://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-016-2917-6en
dc.relation.urlhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974774/en
dc.rightsGreen - can archive pre-print and post-print or publisher's version/PDF
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectCAZymeen
dc.subjectplant pathogenen
dc.subjectanthracnoseen
dc.subjectanthracnose diseaseen
dc.subjectColletotrichumen
dc.subjectfungal genomicsen
dc.subjectC250 Plant Pathologyen
dc.titleGene family expansions and contractions are associated with host range in plant pathogens of the genus Colletotrichumen
dc.typeArticleen
dc.contributor.departmentUniversity of Western Brittanyen
dc.contributor.departmentUniversity of Copenhagenen
dc.contributor.departmentUniversity of Pisaen
dc.contributor.departmentNIAB-EMRen
dc.contributor.departmentUniversity of Warwicken
dc.contributor.departmentUniversity of Salamancaen
dc.contributor.departmentUniversity of Bedfordshireen
dc.identifier.journalBMC Genomicsen
dc.identifier.pmcidPMC4974774
dc.date.updated2019-01-28T11:17:50Z
dc.description.noteoa article
html.description.abstractMany species belonging to the genus Colletotrichum cause anthracnose disease on a wide range of plant species. In addition to their economic impact, the genus Colletotrichum is a useful model for the study of the evolution of host specificity, speciation and reproductive behaviors. Genome projects of Colletotrichum species have already opened a new era for studying the evolution of pathogenesis in fungi. We sequenced and annotated the genomes of four strains in the Colletotrichum acutatum species complex (CAsc), a clade of broad host range pathogens within the genus. The four CAsc proteomes and secretomes along with those representing an additional 13 species (six Colletotrichum spp. and seven other Sordariomycetes) were classified into protein families using a variety of tools. Hierarchical clustering of gene family and functional domain assignments, and phylogenetic analyses revealed lineage specific losses of carbohydrate-active enzymes (CAZymes) and proteases encoding genes in Colletotrichum species that have narrow host range as well as duplications of these families in the CAsc. We also found a lineage specific expansion of necrosis and ethylene-inducing peptide 1 (Nep1)-like protein (NLPs) families within the CAsc. This study illustrates the plasticity of Colletotrichum genomes, and shows that major changes in host range are associated with relatively recent changes in gene content.


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