• Login
    View Item 
    •   Home
    • ISPAR Institute for Sport and Physical Activity Research - to April 2016
    • Applied Sport and Exercise Physiology
    • View Item
    •   Home
    • ISPAR Institute for Sport and Physical Activity Research - to April 2016
    • Applied Sport and Exercise Physiology
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of UOBREPCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsPublisherJournalDepartmentThis CollectionTitleAuthorsIssue DateSubmit DateSubjectsPublisherJournalDepartment

    My Account

    LoginRegister

    About

    AboutLearning ResourcesResearch Graduate SchoolResearch InstitutesUniversity Website

    Statistics

    Display statistics

    An elevation of resting metabolic rate with declining health in nonagenarians may be associated with decreased muscle mass and function in women and men, respectively.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Authors
    Kim, Sangkyu
    Welsh, David A.
    Ravussin, Eric
    Welsch, Michael A.
    Cherry, Katie E.
    Myers, Leann
    Jazwinski, S. Michal
    Affiliation
    Tulane University Health Sciences Center
    Louisiana State University Health Sciences Center
    Pennington Biomedical Research Center
    Louisiana State University
    Issue Date
    2014-06
    Subjects
    age
    aging
    energy metabolism
    frailty
    ageing
    
    Metadata
    Show full item record
    Abstract
    Previously, we showed that FI34, a frailty index based on 34 health and function ability variables, is heritable and a reliable phenotypic indicator of healthy aging. We have now examined the relationship between major components of energy expenditure and the FI34 in participants of the Louisiana Healthy Aging Study. Resting metabolic rate was associated with FI34, even after adjustment for fat-free mass, fat mass, age, sex, thyroid hormones, and insulin-like growth factor 1 levels, in multiple regression analyses. In contrast, there was no association between total daily energy expenditure and FI34. Circulating creatine phosphokinase, a clinical marker of muscle damage, was also significantly associated with FI34. However, these associations of resting metabolic rate with FI34 were restricted to the oldest old (≥90 years) and absent in younger age groups. In oldest old men, the association of FI34 with creatine phosphokinase persisted, whereas in the oldest old women, only the association with resting metabolic rate pertained with the appearance of an effect of body size and composition. These results point toward an increasing metabolic burden for the maintenance of homeodynamics as health declines in nonagenarians, and this has implications for contraction of metabolic reserve that may potentially accelerate the path to disability.
    Citation
    Kim, S. et al (2014) 'An elevation of resting metabolic rate with declining health in nonagenarians may be associated with decreased muscle mass and function in women and men, respectively' J. Gerontol. A Biol. Sci. Med. Sci. 69 (6):650-6
    Publisher
    Oxford University Press
    Journal
    The journals of gerontology. Series A, Biological sciences and medical sciences
    URI
    http://hdl.handle.net/10547/594600
    DOI
    10.1093/gerona/glt150
    PubMed ID
    24162336
    PubMed Central ID
    PMC4022095
    Additional Links
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022095/
    http://biomedgerontology.oxfordjournals.org/content/69/6/650.short
    Type
    Article
    Language
    en
    ISSN
    1758-535X
    ae974a485f413a2113503eed53cd6c53
    10.1093/gerona/glt150
    Scopus Count
    Collections
    Applied Sport and Exercise Physiology

    entitlement

    Related articles

    • Association of healthy aging with parental longevity.
    • Authors: Kim S, Welsh DA, Cherry KE, Myers L, Jazwinski SM
    • Issue date: 2013 Oct
    • Low free testosterone is associated with loss of appendicular muscle mass in Japanese community-dwelling women.
    • Authors: Yuki A, Ando F, Otsuka R, Shimokata H
    • Issue date: 2015 Mar
    • Quantitative measures of healthy aging and biological age.
    • Authors: Kim S, Jazwinski SM
    • Issue date: 2015
    • Muscle function and fat content in relation to sarcopenia, obesity and frailty of old age--An overview.
    • Authors: Buch A, Carmeli E, Boker LK, Marcus Y, Shefer G, Kis O, Berner Y, Stern N
    • Issue date: 2016 Apr
    • Prevalence of sarcopenia among healthy ambulatory subjects: the sarcopenia begins from 45 years.
    • Authors: Cherin P, Voronska E, Fraoucene N, de Jaeger C
    • Issue date: 2014 Apr
    DSpace software (copyright © 2002 - 2021)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.