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    Searching for an operational definition of frailty: a Delphi method based consensus statement: the frailty operative definition-consensus conference project

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    Authors
    Rodríguez-Mañas, Leocadio
    Féart, Catherine
    Mann, Giovanni
    Viña, Jose
    Chatterji, Somnath
    Chodzko-Zajko, Wojtek
    Gonzalez-Colaço Harmand, Magali
    Bergman, Howard
    Carcaillon, Laure
    Nicholson, Caroline
    Scuteri, Angelo
    Sinclair, Alan J.
    Pelaez, Martha
    Van der Cammen, Tischa
    Beland, François
    Bickenbach, Jerome
    Delamarche, Paul
    Ferrucci, Luigi
    Fried, Linda P
    Gutiérrez-Robledo, Luis Miguel
    Rockwood, Kenneth
    Rodríguez Artalejo, Fernando
    Serviddio, Gaetano
    Vega, Enrique
    Show allShow less
    Affiliation
    Hospital Universitario de Getafe, Madrid
    Université Bordeaux
    King’s College, London
    Universidad de Valencia
    World Health Organization
    University of Illinois
    McGill University
    Centre for Research in Epidemiology and Population Health, , France
    INRCA/IRCCS, Roma
    University of Bedfordshire
    Health Foundation of South Florida
    Erasmus University Medical Center
    Lady Davis Hôpital Général Juif, Montreal
    Leiter Unit Disability Policy Schweizer, Nottwill, Switzerland
    University of Rennes
    National institute on Aging, National Institutes of Health
    Columbia University Medical Center
    Instituto de Geriatría, México city
    Dalhousie University
    Universidad Autónoma de Madrid
    University of Foggia
    Pan American Health Organization/World Health Organization
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    Issue Date
    2013-01
    Subjects
    frailty
    consensus definition
    older people
    biomarkers
    
    Metadata
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    Abstract
    Background. There is no consensus regarding the definition of frailty for clinical uses. Methods. A modified Delphi process was used to attempt to achieve consensus definition. Experts were selected from different fields and organized into five Focus Groups. A questionnaire was developed and sent to experts in the area of frailty. Responses and comments were analyzed using a pre-established strategy. Statements with an agreement more than or equal to 80% were accepted. Results. Overall, 44% of the statements regarding the concept of frailty and 18% of the statements regarding diagnostic criteria were accepted. There was consensus on the value of screening for frailty and about the identification of six domains of frailty for inclusion in a clinical definition, but no agreement was reached concerning a specific set of clinical/laboratory biomarkers useful for diagnosis. Conclusions. There is agreement on the usefulness of defining frailty in clinical settings as well as on its main dimensions. However, additional research is needed before an operative definition of frailty can be established.
    Citation
    Rodríguez-Mañas, L. et al (2013) 'Searching for an operational definition of frailty: a Delphi method based consensus statement: the frailty operative definition-consensus conference project' J. Gerontol. A 68 (1):62-7 Biol. Sci. Med. Sci.
    Publisher
    Oxford University Press
    Journal
    The journals of gerontology. Series A, Biological sciences and medical sciences
    URI
    http://hdl.handle.net/10547/593503
    DOI
    10.1093/gerona/gls119
    PubMed ID
    22511289
    PubMed Central ID
    PMC3598366
    Additional Links
    http://biomedgerontology.oxfordjournals.org/content/68/1/62.short
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598366/
    Type
    Article
    Language
    en
    ISSN
    1758-535X
    ae974a485f413a2113503eed53cd6c53
    10.1093/gerona/gls119
    Scopus Count
    Collections
    IHR Institute for Health Research

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