The triglyceride to high-density lipoprotein ratio identifies children who may be at risk of developing cardiometabolic disease
Issue Date
2014-08Subjects
blood pressurecardiometabolic risk
lipoproteins
metabolic syndrome
obesity
C600 Sports Science
cardiometabolic health
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Aim: It is important to develop simple, reliable methods to identify high-risk individuals who may benefit from intervention. This study investigated the association between the triglyceride to high-density lipoprotein cholesterol (TG/HDL) ratio and cardiometabolic risk, cardiorespiratory fitness and physical activity in children. Methods: Anthropometric, biochemical parameters, cardiorespiratory fitness and accelerometry determined physical activity were assessed in 155 children (80 girls) from 10 to 14 years of age from Bedfordshire, UK. Participants were grouped into high and low TG/HDL ratio groups, according to published thresholds. MANCOVA and logistic regression were used in the analysis. Results: Cardiometabolic risk factor levels were significantly higher in participants with a high TG/HDL ratio (p < 0.05). The odds of having high waist circumference (OR = 13.99; 95% CI 2.93, 69.25), elevated systolic blood pressure (5.27; 1.39, 20.01), high non-HDL cholesterol (19.47; 4.42, 85.81) and ≥2 cardiometabolic risk factors (15.32; 3.10, 75.79) were higher in participants with a high TG/HDL ratio. The TG/HDL ratio values were significantly lower in those with high cardiorespiratory fitness (p = 0.01), but there was no association with physical activity. Conclusion: These findings support the use of the TG/HDL ratio to identify children with cardiometabolic risk factors who may be at risk of developing cardiometabolic disease.Citation
Bailey, D.P., Savory, L.A., Jenton, S.J., Davies, B.R., Kerr, C.J. (2014) 'The triglyceride to high-density lipoprotein ratio identifies children who may be at risk of developing cardiometabolic disease' Acta Paediatrica 103 (8):e349Publisher
WileyJournal
Acta PaediatricaPubMed ID
24796207Additional Links
http://doi.wiley.com/10.1111/apa.12677Type
ArticleLanguage
enISSN
0803-5253ae974a485f413a2113503eed53cd6c53
10.1111/apa.12677
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