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    The innovative evolution of cancer gene and cellular therapies

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    Authors
    Lam, P.
    Khan, Ghazala
    Stripecke, R.
    Hui, K.M.
    Kasahara, N.
    Peng, Kah-Whye
    Guinn, Barbara-Ann
    Issue Date
    2013-02-01
    Subjects
    cancer gene therapy
    cancer immunotherapy
    cellular therapy
    
    Metadata
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    Abstract
    We provide an overview of the latest developments in cancer gene therapy--from the bench to early-stage clinical trials. We describe the most recent work of worldwide teams including experienced scientists and clinicians, reflecting the recent emergence of gene therapy from the 'Valley of Death'. The treatment efficacy of clinical gene therapy has now been shown in a number of diseases including cancer and we are observing a renewed interest by big pharmaceutical and biotechnology companies most obviously demonstrated by Amgen's acquisition of Biovex for up to USD$1 billion. There is an opportunity to be cautiously hopeful regarding the future of gene therapy in the clinic and we review here some of the most recent progress in the field.
    Citation
    Lam, P., Khan, G., Stripecke, R., Hui, K.M., Kasahara, N., Peng, K.-W. & Guinn, B.A (2013) 'The innovative evolution of cancer gene and cellular therapies'. Cancer Gene Therapy, 20 (3) pp141-9
    Publisher
    Nature Publishing Group
    Journal
    Cancer Gene Therapy
    URI
    http://hdl.handle.net/10547/578855
    DOI
    10.1038/cgt.2012.93
    Additional Links
    http://www.nature.com/doifinder/10.1038/cgt.2012.93
    Type
    Article
    Language
    en
    ISSN
    0929-1903
    1476-5500
    ae974a485f413a2113503eed53cd6c53
    10.1038/cgt.2012.93
    Scopus Count
    Collections
    Biomedicine and Nutrition Research Group

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