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dc.contributor.authorSamoylova, Tatiana I.en_GB
dc.contributor.authorAhmed, Bushra Y.en_GB
dc.contributor.authorVodyanoy, Vitalyen_GB
dc.contributor.authorMorrison, Nancy E.en_GB
dc.contributor.authorSamoylov, Alexandre M.en_GB
dc.contributor.authorGloba, Ludmila P.en_GB
dc.contributor.authorBaker, Henry J.en_GB
dc.contributor.authorCox, Nancy R.en_GB
dc.date.accessioned2013-09-23T11:54:32Z
dc.date.available2013-09-23T11:54:32Z
dc.date.issued2002
dc.identifier.citationSamoylova T.I., Ahmed B.Y., Vodyanoy V. et al. (2002) 'Targeting peptides for microglia identified via phage display', Journal of Neuroimmunology, 127 (1-2),pp.13-21en_GB
dc.identifier.issn01655728
dc.identifier.doi10.1016/S0165-5728(02)00071-1
dc.identifier.urihttp://hdl.handle.net/10547/302090
dc.description.abstractScreening with a 7-mer phage display peptide library, a panel of cell-targeting peptides for the murine microglial cell line, EOC 20, was recognized. A number of similar, but not identical, sets of sequences representing more than 75% of all the cell line-binding clones were identified. Comparative analysis indicated that motif S/(T) F T/(X) Y W is present in the vast majority of the binding sequences. The selectivity and specificity of the dominant peptide sequence identified for microglia was confirmed using both phage displaying the peptide and the synthetic peptide alone.
dc.language.isoenen
dc.publisherElsevieren_GB
dc.relation.urlhttp://linkinghub.elsevier.com/retrieve/pii/S0165572802000711en_GB
dc.rightsArchived with thanks to Journal of Neuroimmunologyen_GB
dc.titleTargeting peptides for microglia identified via phage displayen
dc.typeArticleen
dc.contributor.departmentAuburn Universityen_GB
dc.identifier.journalJournal of Neuroimmunologyen_GB
html.description.abstractScreening with a 7-mer phage display peptide library, a panel of cell-targeting peptides for the murine microglial cell line, EOC 20, was recognized. A number of similar, but not identical, sets of sequences representing more than 75% of all the cell line-binding clones were identified. Comparative analysis indicated that motif S/(T) F T/(X) Y W is present in the vast majority of the binding sequences. The selectivity and specificity of the dominant peptide sequence identified for microglia was confirmed using both phage displaying the peptide and the synthetic peptide alone.


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