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Expression of calbindin-D28K by reactive astrocytes in gerbil hippocampus after ischaemia

dc.contributor.authorToyoshima, Tetsuhikoen_GB
dc.contributor.authorYamagami, Shinichien_GB
dc.contributor.authorAhmed, Bushra Y.en_GB
dc.contributor.authorJin, Lien_GB
dc.contributor.authorMiyamoto, Osamuen_GB
dc.contributor.authorItano, Toshifumien_GB
dc.contributor.authorTokuda, Masaakien_GB
dc.contributor.authorMatsui, Hidekien_GB
dc.contributor.authorHatase, Osamuen_GB
dc.date.accessioned2013-06-28T10:28:01Z
dc.date.available2013-06-28T10:28:01Z
dc.date.issued1996-09-02
dc.identifier.citationToyoshima T., Yamagami S., Ahmed B.Y., Jin, L., Miyamoto, O., Itano, T., Tokuda, M., Matsui, H., Hatase, O. (1996) 'Expression of calbindin-D28K by reactive astrocytes in gerbil hippocampus after ischaemia', Neuroreport, 7(13),pp.2087-2091.en_GB
dc.identifier.issn0959-4965
dc.identifier.pmid8930964
dc.identifier.urihttp://hdl.handle.net/10547/294868
dc.description.abstractCalbindin-D28K (Calbindin) is a member of the superfamily of calcium-binding proteins that is implicated in the regulation of intracellular calcium. In the adult mammalian brain, calbindin was thought to be present only in neurones, where it is believed to serve a neuroprotective role. We now report the expression of calbindin after ischaemia in reactive astrocytes in the CA1 subfield of the hippocampus. Since other calcium-binding proteins, such as S-100 and calmodulin, which induce transformation or proliferation of glia, occur in astrocytes, it is conceivable that the expression of calbindin after ischaemia might be an important part of the process of gliosis.
dc.language.isoenen
dc.publisherLippincott, Williams & Wilkinsen_GB
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/8930964en_GB
dc.rightsArchived with thanks to Neuroreporten_GB
dc.subject.meshAnimals
dc.subject.meshAstrocytes
dc.subject.meshCalcium-Binding Protein, Vitamin D-Dependent
dc.subject.meshGerbillinae
dc.subject.meshGlial Fibrillary Acidic Protein
dc.subject.meshHippocampus
dc.subject.meshImmunohistochemistry
dc.subject.meshIschemic Attack, Transient
dc.subject.meshNerve Tissue Proteins
dc.subject.meshPyramidal Cells
dc.subject.meshTime Factors
dc.titleExpression of calbindin-D28K by reactive astrocytes in gerbil hippocampus after ischaemiaen
dc.typeArticleen
dc.identifier.journalNeuroreporten_GB
html.description.abstractCalbindin-D28K (Calbindin) is a member of the superfamily of calcium-binding proteins that is implicated in the regulation of intracellular calcium. In the adult mammalian brain, calbindin was thought to be present only in neurones, where it is believed to serve a neuroprotective role. We now report the expression of calbindin after ischaemia in reactive astrocytes in the CA1 subfield of the hippocampus. Since other calcium-binding proteins, such as S-100 and calmodulin, which induce transformation or proliferation of glia, occur in astrocytes, it is conceivable that the expression of calbindin after ischaemia might be an important part of the process of gliosis.


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