G-CSF rescues tumor growth and neo-angiogenesis during liver metastasis under host angiopoietin-2 deficiency
Authors
Im, Jae HongTapmeier, Thomas
Balathasan, Lukxmi
Gal, Annamaria
Yameen, Sabira
Hill, Sally
Smart, Sean
Noterdaeme, Olivier
Kelly, Matthew
Brady, Michael
Fu, Weili
Kruse, Karoline
Bernhard, Eric J.
Augustin, Hellmut G.
Muschel, Ruth J.
Issue Date
2013
Metadata
Show full item recordAbstract
Suppression of neo-angiogenesis is a clinically used anti-tumor strategy with new targets such as angiopoietin-2 (Ang2) being proposed. However, the functions of Ang2 in vascular remodeling, inflammation and tumor growth are not consistent. We examined effect of depletion of host Ang2 on liver colony formation using Ang2 deficient (Ang22/2) mice.Citation
Im, J.H., Tapmeier, T., Balathasan, L., Gal, A., Yameen, S., Hill, S., Smart, S., Noterdaeme, O., Kelly, M., Brady, M., Fu, W., Kruse, K., Bernhard, E.J., Augustin, H.G. and Muschel, R.J. (2013) 'G-CSF rescues tumor growth and neo-angiogenesis during liver metastasis under host angiopoietin-2 deficiency', International Journal of Cancer, 132(2), pp.315-326.Publisher
WileyJournal
International Journal of CancerAdditional Links
http://doi.wiley.com/10.1002/ijc.27677Type
ArticleLanguage
enISSN
0020-7136ae974a485f413a2113503eed53cd6c53
10.1002/ijc.27677