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    The virtual physiological human — a European initiative for in silico human modelling

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    Authors
    Viceconti, Marco
    Clapworthy, Gordon J.
    Jan, Serge Van Sint
    Issue Date
    2008-12
    Subjects
    integrative research
    multiscale modelling
    musculoskeletal system
    physiome
    virtual physiological human
    
    Metadata
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    Abstract
    The Virtual Physiological Human (VPH) is an initiative, strongly supported by the European Commission (EC), that seeks to develop an integrated model of human physiology at multiple scales from the whole body through the organ, tissue, cell and molecular levels to the genomic level. VPH had its beginnings in 2005 with informal discussions amongst like-minded scientists, which led to the STEP project, a Coordination Action funded by the EC that began in early 2006. The STEP project greatly accelerated the progress of the VPH and proved to be a catalyst for wide-ranging discussions within Europe and for outreach activities designed to develop a broad international approach to the huge scientific and technological challenges involved in this area. This paper provides an overview of the VPH and the developments it has engendered in the rapidly expanding worldwide activities associated with the physiome. It then uses one particular project, the Living Human Project, to illustrate the type of advances that are taking place to further the aims of the VPH and similar initiatives worldwide.
    Citation
    Viceconti, M., Clapworthy, G., Jan, S. (2008) 'The Virtual Physiological Human — A European Initiative for in silico Human Modelling' The Journal of Physiological Sciences 58 (7): 441-446
    Publisher
    Physiological Society of Japan
    Journal
    The Journal of Physiological Sciences
    URI
    http://hdl.handle.net/10547/223732
    DOI
    10.2170/physiolsci.RP009908
    Additional Links
    http://joi.jlc.jst.go.jp/JST.JSTAGE/physiolsci/RP009908?from=CrossRef
    Type
    Article
    Language
    en
    ISSN
    1880-6546
    1880-6562
    ae974a485f413a2113503eed53cd6c53
    10.2170/physiolsci.RP009908
    Scopus Count
    Collections
    Centre for Computer Graphics and Visualisation (CCGV)

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