Brain activation in highly superior autobiographical memory: the role of the praecuneus in the autobiographical memory retrieval network

2.50
Hdl Handle:
http://hdl.handle.net/10547/623238
Title:
Brain activation in highly superior autobiographical memory: the role of the praecuneus in the autobiographical memory retrieval network
Authors:
Mazzoni, Giuliana; Clark, Andrew; De Bartolo, Adriana; Guerrini, Chiara; Nahouli, Zacharia; Duzzi, Davide; De Marco, Matteo; McGeown, William; Venneri, Annalena
Abstract:
This is the first study to examine functional brain activation in a single case of Highly Superior Autobiographical Memory (HSAM) who shows no sign of obsessive compulsive disorder (OCD). While previous work has documented the existence of HSAM, information about brain areas involved in this exceptional form of memory for personal events relies on structural and resting state connectivity data, with mixed results so far. In this first taskbased functional magnetic resonance Imaging (fMRI) study of a normal individual with HSAM, dates were presented as cues and two phases were assessed during memory retrieval, initial access and later elaboration. Results showed that initial access was very fast, did not activate the hippocampus, and involved activation of predominantly posterior visual areas, including the praecuneus. These areas typically become active during later stages of elaboration of personal memories rather than during initial access. Elaboration involved a balanced bilateral activation of most of the autobiographical network areas, rather than the more typical shifts observed in people without HSAM. Overall, the pattern of brain activations, which rests on repeated observations in a single individual, highlights a strong involvement of the praecuneus and an idiosyncratic initial access to personal memory representations. Implications for the nature of personal memories in HSAM are discussed.
Affiliation:
University La Sapienza; University of Hull; University of Bedfordshire; University of Westminster; Universita' di Modena e Reggio Emilia; University of Sheffield; University of Strathclyde
Citation:
Mazzoni G, Clark A, De Bartolo A, Guerrini C, Nahouli Z, Duzzi D, De Marco M, McGeown W, Venneri A (2019) 'Brain activation in highly superior autobiographical memory: the role of the praecuneus in the autobiographical memory retrieval network', Cortex, (), pp.-.
Publisher:
Elsevier
Journal:
Cortex
Issue Date:
5-Mar-2019
URI:
http://hdl.handle.net/10547/623238
DOI:
10.1016/j.cortex.2019.02.020
PubMed ID:
30926140
Additional Links:
https://www.sciencedirect.com/science/article/pii/S0010945219300887
Type:
Article
Language:
en
ISSN:
0010-9452
Appears in Collections:
Psychology

Full metadata record

DC FieldValue Language
dc.contributor.authorMazzoni, Giulianaen
dc.contributor.authorClark, Andrewen
dc.contributor.authorDe Bartolo, Adrianaen
dc.contributor.authorGuerrini, Chiaraen
dc.contributor.authorNahouli, Zachariaen
dc.contributor.authorDuzzi, Davideen
dc.contributor.authorDe Marco, Matteoen
dc.contributor.authorMcGeown, Williamen
dc.contributor.authorVenneri, Annalenaen
dc.date.accessioned2019-04-15T10:40:00Z-
dc.date.available2019-04-15T10:40:00Z-
dc.date.issued2019-03-05-
dc.identifier.citationMazzoni G, Clark A, De Bartolo A, Guerrini C, Nahouli Z, Duzzi D, De Marco M, McGeown W, Venneri A (2019) 'Brain activation in highly superior autobiographical memory: the role of the praecuneus in the autobiographical memory retrieval network', Cortex, (), pp.-.en
dc.identifier.issn0010-9452-
dc.identifier.pmid30926140-
dc.identifier.doi10.1016/j.cortex.2019.02.020-
dc.identifier.urihttp://hdl.handle.net/10547/623238-
dc.description.abstractThis is the first study to examine functional brain activation in a single case of Highly Superior Autobiographical Memory (HSAM) who shows no sign of obsessive compulsive disorder (OCD). While previous work has documented the existence of HSAM, information about brain areas involved in this exceptional form of memory for personal events relies on structural and resting state connectivity data, with mixed results so far. In this first taskbased functional magnetic resonance Imaging (fMRI) study of a normal individual with HSAM, dates were presented as cues and two phases were assessed during memory retrieval, initial access and later elaboration. Results showed that initial access was very fast, did not activate the hippocampus, and involved activation of predominantly posterior visual areas, including the praecuneus. These areas typically become active during later stages of elaboration of personal memories rather than during initial access. Elaboration involved a balanced bilateral activation of most of the autobiographical network areas, rather than the more typical shifts observed in people without HSAM. Overall, the pattern of brain activations, which rests on repeated observations in a single individual, highlights a strong involvement of the praecuneus and an idiosyncratic initial access to personal memory representations. Implications for the nature of personal memories in HSAM are discussed.en
dc.language.isoenen
dc.publisherElsevieren
dc.relation.urlhttps://www.sciencedirect.com/science/article/pii/S0010945219300887en
dc.rightsGreen - can archive pre-print and post-print or publisher's version/PDF-
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectautobiographical memory networken
dc.subjectbrain imagingen
dc.subjecthighly superior autobiographical memory (HSAM)en
dc.subjectpraecuneusen
dc.subjectmemoryen
dc.subjectC860 Neuropsychologyen
dc.titleBrain activation in highly superior autobiographical memory: the role of the praecuneus in the autobiographical memory retrieval networken
dc.typeArticleen
dc.contributor.departmentUniversity La Sapienzaen
dc.contributor.departmentUniversity of Hullen
dc.contributor.departmentUniversity of Bedfordshireen
dc.contributor.departmentUniversity of Westminsteren
dc.contributor.departmentUniversita' di Modena e Reggio Emiliaen
dc.contributor.departmentUniversity of Sheffielden
dc.contributor.departmentUniversity of Strathclydeen
dc.identifier.journalCortexen
dc.date.updated2019-04-15T10:35:46Z-
dc.description.note12 months from pub date-

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