In vitro bioaccessibility and physicochemical properties of phytosterol linoleic ester synthesized from soybean sterol and linoleic acid

2.50
Hdl Handle:
http://hdl.handle.net/10547/622511
Title:
In vitro bioaccessibility and physicochemical properties of phytosterol linoleic ester synthesized from soybean sterol and linoleic acid
Authors:
Yang, Fuming; Oyeyinka, Samson A. ( 0000-0002-5760-541X ) ; Xu, Weili ( 0000-0002-6786-4124 ) ; Ma, Ying ( 0000-0002-2641-7926 ) ; Zhou, Shaobo ( 0000-0001-5214-2973 )
Abstract:
Phytosterols are bioactive components capable of reducing cholesterol level in serum and reducing risk of arteriosclerosis. In this study, conditions for the synthesis of maximum yield of phytosterol linoleic ester (PLE) was optimized and the physicochemical properties and in vitro bioaccessibility of the PLE were assessed. Under the optimized condition of 1:1.1 mol ratio of phytosterol and linoleoyl chloride at 80 °C for 1.5 h, the conversion rate of phytosterol reached 96.1%. Its solubility in oil increased 20 times, up to 33.8%. Also, peroxide value of PLE was much lower than linoleic acid (32.9 and 47.0 mmol/kg), which means better oxidative stability. Bioaccessibility of PLE was affected by time, concentration of bile extract, and dissolved medium. It was 4.93% alone, increased by 2.5 times compare to phytosterol; or 53.46% in oil, under the condition of 40 mg/mL bile extract for 120 min. In conclusion, under the tested condition, phytosterol conversion rate, its solubility in oil and bioaccessibility were improved significantly. The method showed great potential in manufacture high quality and quantity of PLE.
Affiliation:
Harbin Institute of Technology; University of Ilorin; University of Bedfordshire
Citation:
Yang F, Oyeyinka SA, Xu W, Ma Y, Zhou S (2018) 'In vitro bioaccessibility and physicochemical properties of phytosterol linoleic ester synthesized from soybean sterol and linoleic acid', LWT - food science and technology, 92 (2), pp.265-271.
Publisher:
Elsevier
Journal:
LWT - food science and technology
Issue Date:
14-Feb-2018
URI:
http://hdl.handle.net/10547/622511
DOI:
10.1016/j.lwt.2018.02.031
Additional Links:
https://www.sciencedirect.com/science/article/pii/S0023643818301609
Type:
Article
Language:
en
ISSN:
0023-6438
EISSN:
0023-6438
Appears in Collections:
Biomedical and biological science

Full metadata record

DC FieldValue Language
dc.contributor.authorYang, Fumingen
dc.contributor.authorOyeyinka, Samson A.en
dc.contributor.authorXu, Weilien
dc.contributor.authorMa, Yingen
dc.contributor.authorZhou, Shaoboen
dc.date.accessioned2018-02-27T09:40:29Z-
dc.date.available2018-02-27T09:40:29Z-
dc.date.issued2018-02-14-
dc.identifier.citationYang F, Oyeyinka SA, Xu W, Ma Y, Zhou S (2018) 'In vitro bioaccessibility and physicochemical properties of phytosterol linoleic ester synthesized from soybean sterol and linoleic acid', LWT - food science and technology, 92 (2), pp.265-271.en
dc.identifier.issn0023-6438-
dc.identifier.doi10.1016/j.lwt.2018.02.031-
dc.identifier.urihttp://hdl.handle.net/10547/622511-
dc.description.abstractPhytosterols are bioactive components capable of reducing cholesterol level in serum and reducing risk of arteriosclerosis. In this study, conditions for the synthesis of maximum yield of phytosterol linoleic ester (PLE) was optimized and the physicochemical properties and in vitro bioaccessibility of the PLE were assessed. Under the optimized condition of 1:1.1 mol ratio of phytosterol and linoleoyl chloride at 80 °C for 1.5 h, the conversion rate of phytosterol reached 96.1%. Its solubility in oil increased 20 times, up to 33.8%. Also, peroxide value of PLE was much lower than linoleic acid (32.9 and 47.0 mmol/kg), which means better oxidative stability. Bioaccessibility of PLE was affected by time, concentration of bile extract, and dissolved medium. It was 4.93% alone, increased by 2.5 times compare to phytosterol; or 53.46% in oil, under the condition of 40 mg/mL bile extract for 120 min. In conclusion, under the tested condition, phytosterol conversion rate, its solubility in oil and bioaccessibility were improved significantly. The method showed great potential in manufacture high quality and quantity of PLE.en
dc.language.isoenen
dc.publisherElsevieren
dc.relation.urlhttps://www.sciencedirect.com/science/article/pii/S0023643818301609en
dc.rightsGreen - can archive pre-print and post-print or publisher's version/PDF-
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectphytosterolen
dc.subjectlinoleic aciden
dc.subjectbioaccessibilityen
dc.subjectphytosterol linoleic esteren
dc.subjectD610 Food Scienceen
dc.titleIn vitro bioaccessibility and physicochemical properties of phytosterol linoleic ester synthesized from soybean sterol and linoleic aciden
dc.typeArticleen
dc.identifier.eissn0023-6438-
dc.contributor.departmentHarbin Institute of Technologyen
dc.contributor.departmentUniversity of Ilorinen
dc.contributor.departmentUniversity of Bedfordshireen
dc.identifier.journalLWT - food science and technologyen
dc.date.updated2018-02-27T09:28:09Z-
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