The role of zinc in renal pathological changes in diabetic status

2.50
Hdl Handle:
http://hdl.handle.net/10547/622233
Title:
The role of zinc in renal pathological changes in diabetic status
Authors:
Fernando, Julie; Zhou, Shaobo ( 0000-0001-5214-2973 )
Abstract:
Diabetes mellitus (DM) was the 8th leading cause of death in 2011, resulting in 1.4 million deaths worldwide. One of the complications of DM is chronic kidney disease, which accounts for nearly 44% of all new cases of kidney failure in the US in 2011. Zinc (Zn), an essential trace element, plays an important role in regulating carbohydrate metabolism. Several studies have shown the beneficial effects of Zn on renal pathological changes in Type 1 and Type 2 diabetic subjects, by reducing levels of oxidative stress, glomerular damage, and urinary albumin excretion after Zn supplementation. In contrast, other studies have shown little effects of Zn supplementation on renal damage. This paper reviewed recent research developments and found promising results of Zn in reducing, and in some cases, completely preventing renal damage. Nevertheless, the use of Zn as a potential treatment and especially its long-term impact against renal pathological symptoms in DM patients needs to be further studied.
Affiliation:
University of Bedfordshire
Citation:
Fernando J, Zhou S (2015) 'The role of zinc in renal pathological changes in diabetic status', Journal of Nutritional Disorders & Therapy, 5 (3).
Publisher:
OMICS International
Journal:
Journal of Nutritional Disorders & Therapy
Issue Date:
13-Jun-2015
URI:
http://hdl.handle.net/10547/622233
DOI:
10.4172/2161-0509.1000165
Additional Links:
https://www.omicsonline.org/open-access/the-role-of-zinc-in-renal-pathological-changes-in-diabetic-status-2161-0509-1000165.php?aid=53533
Type:
Article
Language:
en
ISSN:
2161-0509
EISSN:
2161-0509
Appears in Collections:
Biomedical and biological science

Full metadata record

DC FieldValue Language
dc.contributor.authorFernando, Julieen
dc.contributor.authorZhou, Shaoboen
dc.date.accessioned2017-09-25T11:39:02Z-
dc.date.available2017-09-25T11:39:02Z-
dc.date.issued2015-06-13-
dc.identifier.citationFernando J, Zhou S (2015) 'The role of zinc in renal pathological changes in diabetic status', Journal of Nutritional Disorders & Therapy, 5 (3).en
dc.identifier.issn2161-0509-
dc.identifier.doi10.4172/2161-0509.1000165-
dc.identifier.urihttp://hdl.handle.net/10547/622233-
dc.description.abstractDiabetes mellitus (DM) was the 8th leading cause of death in 2011, resulting in 1.4 million deaths worldwide. One of the complications of DM is chronic kidney disease, which accounts for nearly 44% of all new cases of kidney failure in the US in 2011. Zinc (Zn), an essential trace element, plays an important role in regulating carbohydrate metabolism. Several studies have shown the beneficial effects of Zn on renal pathological changes in Type 1 and Type 2 diabetic subjects, by reducing levels of oxidative stress, glomerular damage, and urinary albumin excretion after Zn supplementation. In contrast, other studies have shown little effects of Zn supplementation on renal damage. This paper reviewed recent research developments and found promising results of Zn in reducing, and in some cases, completely preventing renal damage. Nevertheless, the use of Zn as a potential treatment and especially its long-term impact against renal pathological symptoms in DM patients needs to be further studied.en
dc.language.isoenen
dc.publisherOMICS Internationalen
dc.relation.urlhttps://www.omicsonline.org/open-access/the-role-of-zinc-in-renal-pathological-changes-in-diabetic-status-2161-0509-1000165.php?aid=53533en
dc.rightsBlue - can archive post-print (ie final draft post-refereeing) or publisher's version/PDF-
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectzincen
dc.subjectdiabetesen
dc.titleThe role of zinc in renal pathological changes in diabetic statusen
dc.typeArticleen
dc.identifier.eissn2161-0509-
dc.contributor.departmentUniversity of Bedfordshireen
dc.identifier.journalJournal of Nutritional Disorders & Therapyen
dc.date.updated2017-09-25T11:16:37Z-
dc.description.noteopen access-
This item is licensed under a Creative Commons License
Creative Commons
All Items in UOBREP are protected by copyright, with all rights reserved, unless otherwise indicated.