The triglyceride to high-density lipoprotein ratio identifies children who may be at risk of developing cardiometabolic disease

2.50
Hdl Handle:
http://hdl.handle.net/10547/582426
Title:
The triglyceride to high-density lipoprotein ratio identifies children who may be at risk of developing cardiometabolic disease
Authors:
Bailey, Daniel Paul ( 0000-0003-3772-630X ) ; Savory, Louise A.; Denton, Sarah J.; Davies, Ben R.; Kerr, Catherine J.
Abstract:
Aim: It is important to develop simple, reliable methods to identify high-risk individuals who may benefit from intervention. This study investigated the association between the triglyceride to high-density lipoprotein cholesterol (TG/HDL) ratio and cardiometabolic risk, cardiorespiratory fitness and physical activity in children. Methods: Anthropometric, biochemical parameters, cardiorespiratory fitness and accelerometry determined physical activity were assessed in 155 children (80 girls) from 10 to 14 years of age from Bedfordshire, UK. Participants were grouped into high and low TG/HDL ratio groups, according to published thresholds. MANCOVA and logistic regression were used in the analysis. Results: Cardiometabolic risk factor levels were significantly higher in participants with a high TG/HDL ratio (p < 0.05). The odds of having high waist circumference (OR = 13.99; 95% CI 2.93, 69.25), elevated systolic blood pressure (5.27; 1.39, 20.01), high non-HDL cholesterol (19.47; 4.42, 85.81) and ≥2 cardiometabolic risk factors (15.32; 3.10, 75.79) were higher in participants with a high TG/HDL ratio. The TG/HDL ratio values were significantly lower in those with high cardiorespiratory fitness (p = 0.01), but there was no association with physical activity. Conclusion: These findings support the use of the TG/HDL ratio to identify children with cardiometabolic risk factors who may be at risk of developing cardiometabolic disease.
Affiliation:
University of Bedfordshire; Newcastle University; Oxford Brookes University
Citation:
Bailey, D.P., Savory, L.A., Jenton, S.J., Davies, B.R., Kerr, C.J. (2014) 'The triglyceride to high-density lipoprotein ratio identifies children who may be at risk of developing cardiometabolic disease' Acta Paediatrica 103 (8):e349
Publisher:
Wiley
Journal:
Acta Paediatrica
Issue Date:
Aug-2014
URI:
http://hdl.handle.net/10547/582426
DOI:
10.1111/apa.12677
PubMed ID:
24796207
Additional Links:
http://doi.wiley.com/10.1111/apa.12677
Type:
Article
Language:
en
ISSN:
0803-5253
Appears in Collections:
Physical Activity and Health

Full metadata record

DC FieldValue Language
dc.contributor.authorBailey, Daniel Paulen
dc.contributor.authorSavory, Louise A.en
dc.contributor.authorDenton, Sarah J.en
dc.contributor.authorDavies, Ben R.en
dc.contributor.authorKerr, Catherine J.en
dc.date.accessioned2015-11-20T12:34:19Zen
dc.date.available2015-11-20T12:34:19Zen
dc.date.issued2014-08en
dc.identifier.citationBailey, D.P., Savory, L.A., Jenton, S.J., Davies, B.R., Kerr, C.J. (2014) 'The triglyceride to high-density lipoprotein ratio identifies children who may be at risk of developing cardiometabolic disease' Acta Paediatrica 103 (8):e349en
dc.identifier.issn0803-5253en
dc.identifier.pmid24796207en
dc.identifier.doi10.1111/apa.12677en
dc.identifier.urihttp://hdl.handle.net/10547/582426en
dc.description.abstractAim: It is important to develop simple, reliable methods to identify high-risk individuals who may benefit from intervention. This study investigated the association between the triglyceride to high-density lipoprotein cholesterol (TG/HDL) ratio and cardiometabolic risk, cardiorespiratory fitness and physical activity in children. Methods: Anthropometric, biochemical parameters, cardiorespiratory fitness and accelerometry determined physical activity were assessed in 155 children (80 girls) from 10 to 14 years of age from Bedfordshire, UK. Participants were grouped into high and low TG/HDL ratio groups, according to published thresholds. MANCOVA and logistic regression were used in the analysis. Results: Cardiometabolic risk factor levels were significantly higher in participants with a high TG/HDL ratio (p < 0.05). The odds of having high waist circumference (OR = 13.99; 95% CI 2.93, 69.25), elevated systolic blood pressure (5.27; 1.39, 20.01), high non-HDL cholesterol (19.47; 4.42, 85.81) and ≥2 cardiometabolic risk factors (15.32; 3.10, 75.79) were higher in participants with a high TG/HDL ratio. The TG/HDL ratio values were significantly lower in those with high cardiorespiratory fitness (p = 0.01), but there was no association with physical activity. Conclusion: These findings support the use of the TG/HDL ratio to identify children with cardiometabolic risk factors who may be at risk of developing cardiometabolic disease.en
dc.language.isoenen
dc.publisherWileyen
dc.relation.urlhttp://doi.wiley.com/10.1111/apa.12677en
dc.rightsArchived with thanks to Acta Paediatricaen
dc.subjectblood pressureen
dc.subjectcardiometabolic risken
dc.subjectlipoproteinsen
dc.subjectmetabolic syndromeen
dc.subjectobesityen
dc.subjectC600 Sports Scienceen
dc.subjectcardiometabolic healthen
dc.titleThe triglyceride to high-density lipoprotein ratio identifies children who may be at risk of developing cardiometabolic diseaseen
dc.typeArticleen
dc.contributor.departmentUniversity of Bedfordshireen
dc.contributor.departmentNewcastle Universityen
dc.contributor.departmentOxford Brookes Universityen
dc.identifier.journalActa Paediatricaen
dc.contributor.institutionUniversity of Bedfordshireen
dc.contributor.institutionNewcastle Universityen
dc.contributor.institutionUniversity of Bristolen
dc.contributor.institutionOxford Brookes Universityen

Related articles on PubMed

This item is licensed under a Creative Commons License
Creative Commons
All Items in UOBREP are protected by copyright, with all rights reserved, unless otherwise indicated.