There are currently four main research themes within the Group: Metal binding to the prion protein, its effect on protein conformation and aggregation, and possible links to CJD and mad cow disease. Molecular and cellular mechanisms underlying neurodegenerative disorders including Parkinson’s disease, epilepsy and Alzheimer’s disease. Interactions of microorganisms and free living amoeba with the blood brain barrier to cause encephalitis and the use of Acanthamoeba aminopeptidases as a target for treatment. Applied proteomics and applied metabolomic techniques in nutritional metabolism research. Personnel These themes complement the research in biomedical science under the thematic areas of health and wellbeing, and disease and aging. The strategy for the environmental science area aligns with the iBEST's future strategy which has these key objectives: Enhance our reputation as leaders in national and international environmental change management research agendas and contribute to socio-economic development Further develop and support collaborative and interdisciplinary research and enterprise opportunities both within (e.g. inter-institute collaborations) and outwith the University (e.g. organisations involved in research, policy and practice) Grow PG-R student activity and the research base to further develop a platform for sustainable research income Create a Centre/Network for Interdisciplinary Research and Training that would serve as a vehicle to develop innovation systems research and impact in food, health and the environment areas Further develop systems and implementation processes that effectively support research and enterprise activity of our academic staff.

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