Caspase-2 and caspase-8 trigger caspase-3 activation following 6-OHDA-induced stress in human dopaminergic neurons differentiated from ReNVM stem cells

2.50
Hdl Handle:
http://hdl.handle.net/10547/302101
Title:
Caspase-2 and caspase-8 trigger caspase-3 activation following 6-OHDA-induced stress in human dopaminergic neurons differentiated from ReNVM stem cells
Authors:
Chaudhry, Zahara Latif; Ahmed, Bushra Y.
Abstract:
The purpose of the study was to establish a suitable model to study Parkinson’s disease (PD) pathogenesis in differentiated dopaminergic neurons (dDCN). The specific aim was to demonstrate the involvement of the caspase family and to identify specific caspases which are activated by 6-hydroxydopamine (6OHD) treatment leading to death of dDCN.
Citation:
Chaudhry, Z.L. and Ahmed, B.Y. (2012) 'Caspase-2 and caspase-8 trigger caspase-3 activation following 6-OHDA-induced stress in human dopaminergic neurons differentiated from ReNVM stem cells', Neurological Research 35(4) 435-440
Publisher:
Maney Publishing
Journal:
Neurological Research
Issue Date:
2012
URI:
http://hdl.handle.net/10547/302101
DOI:
10.1179/1743132812Y.0000000135a
Additional Links:
http://www.ingentaconnect.com/content/maney/nres/pre-prints/1743132812Y.0000000135a
Type:
Article
Language:
en
ISSN:
0161-6412
Appears in Collections:
Cell and Cryobiology Research Group

Full metadata record

DC FieldValue Language
dc.contributor.authorChaudhry, Zahara Latifen_GB
dc.contributor.authorAhmed, Bushra Y.en_GB
dc.date.accessioned2013-09-23T11:45:31Zen
dc.date.available2013-09-23T11:45:31Zen
dc.date.issued2012en
dc.identifier.citationChaudhry, Z.L. and Ahmed, B.Y. (2012) 'Caspase-2 and caspase-8 trigger caspase-3 activation following 6-OHDA-induced stress in human dopaminergic neurons differentiated from ReNVM stem cells', Neurological Research 35(4) 435-440en_GB
dc.identifier.issn0161-6412en
dc.identifier.doi10.1179/1743132812Y.0000000135aen
dc.identifier.urihttp://hdl.handle.net/10547/302101en
dc.description.abstractThe purpose of the study was to establish a suitable model to study Parkinson’s disease (PD) pathogenesis in differentiated dopaminergic neurons (dDCN). The specific aim was to demonstrate the involvement of the caspase family and to identify specific caspases which are activated by 6-hydroxydopamine (6OHD) treatment leading to death of dDCN.en_GB
dc.language.isoenen
dc.publisherManey Publishingen_GB
dc.relation.urlhttp://www.ingentaconnect.com/content/maney/nres/pre-prints/1743132812Y.0000000135aen_GB
dc.rightsArchived with thanks to Neurological Researchen_GB
dc.subjectdopaminergic neuronen_GB
dc.subjectcaspaseen_GB
dc.subjectReNcell VMen_GB
dc.subjectParkinson's diseaseen_GB
dc.titleCaspase-2 and caspase-8 trigger caspase-3 activation following 6-OHDA-induced stress in human dopaminergic neurons differentiated from ReNVM stem cellsen
dc.typeArticleen
dc.identifier.journalNeurological Researchen_GB
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