2.50
Hdl Handle:
http://hdl.handle.net/10547/302090
Title:
Targeting peptides for microglia identified via phage display
Authors:
Samoylova, Tatiana I.; Ahmed, Bushra Y.; Vodyanoy, Vitaly; Morrison, Nancy E.; Samoylov, Alexandre M.; Globa, Ludmila P.; Baker, Henry J.; Cox, Nancy R.
Abstract:
Screening with a 7-mer phage display peptide library, a panel of cell-targeting peptides for the murine microglial cell line, EOC 20, was recognized. A number of similar, but not identical, sets of sequences representing more than 75% of all the cell line-binding clones were identified. Comparative analysis indicated that motif S/(T) F T/(X) Y W is present in the vast majority of the binding sequences. The selectivity and specificity of the dominant peptide sequence identified for microglia was confirmed using both phage displaying the peptide and the synthetic peptide alone.
Affiliation:
Auburn University
Citation:
Samoylova T.I., Ahmed B.Y., Vodyanoy V. et al. (2002) 'Targeting peptides for microglia identified via phage display', Journal of Neuroimmunology, 127 (1-2),pp.13-21
Publisher:
Elsevier
Journal:
Journal of Neuroimmunology
Issue Date:
2002
URI:
http://hdl.handle.net/10547/302090
DOI:
10.1016/S0165-5728(02)00071-1
Additional Links:
http://linkinghub.elsevier.com/retrieve/pii/S0165572802000711
Type:
Article
Language:
en
ISSN:
01655728
Appears in Collections:
Cell and Cryobiology Research Group

Full metadata record

DC FieldValue Language
dc.contributor.authorSamoylova, Tatiana I.en_GB
dc.contributor.authorAhmed, Bushra Y.en_GB
dc.contributor.authorVodyanoy, Vitalyen_GB
dc.contributor.authorMorrison, Nancy E.en_GB
dc.contributor.authorSamoylov, Alexandre M.en_GB
dc.contributor.authorGloba, Ludmila P.en_GB
dc.contributor.authorBaker, Henry J.en_GB
dc.contributor.authorCox, Nancy R.en_GB
dc.date.accessioned2013-09-23T11:54:32Z-
dc.date.available2013-09-23T11:54:32Z-
dc.date.issued2002-
dc.identifier.citationSamoylova T.I., Ahmed B.Y., Vodyanoy V. et al. (2002) 'Targeting peptides for microglia identified via phage display', Journal of Neuroimmunology, 127 (1-2),pp.13-21en_GB
dc.identifier.issn01655728-
dc.identifier.doi10.1016/S0165-5728(02)00071-1-
dc.identifier.urihttp://hdl.handle.net/10547/302090-
dc.description.abstractScreening with a 7-mer phage display peptide library, a panel of cell-targeting peptides for the murine microglial cell line, EOC 20, was recognized. A number of similar, but not identical, sets of sequences representing more than 75% of all the cell line-binding clones were identified. Comparative analysis indicated that motif S/(T) F T/(X) Y W is present in the vast majority of the binding sequences. The selectivity and specificity of the dominant peptide sequence identified for microglia was confirmed using both phage displaying the peptide and the synthetic peptide alone.en_GB
dc.language.isoenen
dc.publisherElsevieren_GB
dc.relation.urlhttp://linkinghub.elsevier.com/retrieve/pii/S0165572802000711en_GB
dc.rightsArchived with thanks to Journal of Neuroimmunologyen_GB
dc.titleTargeting peptides for microglia identified via phage displayen
dc.typeArticleen
dc.contributor.departmentAuburn Universityen_GB
dc.identifier.journalJournal of Neuroimmunologyen_GB
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