2.50
Hdl Handle:
http://hdl.handle.net/10547/294868
Title:
Expression of calbindin-D28K by reactive astrocytes in gerbil hippocampus after ischaemia
Authors:
Toyoshima, Tetsuhiko; Yamagami, Shinichi; Ahmed, Bushra Y.; Jin, Li; Miyamoto, Osamu; Itano, Toshifumi; Tokuda, Masaaki; Matsui, Hideki; Hatase, Osamu
Abstract:
Calbindin-D28K (Calbindin) is a member of the superfamily of calcium-binding proteins that is implicated in the regulation of intracellular calcium. In the adult mammalian brain, calbindin was thought to be present only in neurones, where it is believed to serve a neuroprotective role. We now report the expression of calbindin after ischaemia in reactive astrocytes in the CA1 subfield of the hippocampus. Since other calcium-binding proteins, such as S-100 and calmodulin, which induce transformation or proliferation of glia, occur in astrocytes, it is conceivable that the expression of calbindin after ischaemia might be an important part of the process of gliosis.
Citation:
Toyoshima T., Yamagami S., Ahmed B.Y., Jin, L., Miyamoto, O., Itano, T., Tokuda, M., Matsui, H., Hatase, O. (1996) 'Expression of calbindin-D28K by reactive astrocytes in gerbil hippocampus after ischaemia', Neuroreport, 7(13),pp.2087-2091.
Publisher:
Lippincott, Williams & Wilkins
Journal:
Neuroreport
Issue Date:
2-Sep-1996
URI:
http://hdl.handle.net/10547/294868
PubMed ID:
8930964
Additional Links:
http://www.ncbi.nlm.nih.gov/pubmed/8930964
Type:
Article
Language:
en
ISSN:
0959-4965
Appears in Collections:
Cell and Cryobiology Research Group

Full metadata record

DC FieldValue Language
dc.contributor.authorToyoshima, Tetsuhikoen_GB
dc.contributor.authorYamagami, Shinichien_GB
dc.contributor.authorAhmed, Bushra Y.en_GB
dc.contributor.authorJin, Lien_GB
dc.contributor.authorMiyamoto, Osamuen_GB
dc.contributor.authorItano, Toshifumien_GB
dc.contributor.authorTokuda, Masaakien_GB
dc.contributor.authorMatsui, Hidekien_GB
dc.contributor.authorHatase, Osamuen_GB
dc.date.accessioned2013-06-28T10:28:01Z-
dc.date.available2013-06-28T10:28:01Z-
dc.date.issued1996-09-02-
dc.identifier.citationToyoshima T., Yamagami S., Ahmed B.Y., Jin, L., Miyamoto, O., Itano, T., Tokuda, M., Matsui, H., Hatase, O. (1996) 'Expression of calbindin-D28K by reactive astrocytes in gerbil hippocampus after ischaemia', Neuroreport, 7(13),pp.2087-2091.en_GB
dc.identifier.issn0959-4965-
dc.identifier.pmid8930964-
dc.identifier.urihttp://hdl.handle.net/10547/294868-
dc.description.abstractCalbindin-D28K (Calbindin) is a member of the superfamily of calcium-binding proteins that is implicated in the regulation of intracellular calcium. In the adult mammalian brain, calbindin was thought to be present only in neurones, where it is believed to serve a neuroprotective role. We now report the expression of calbindin after ischaemia in reactive astrocytes in the CA1 subfield of the hippocampus. Since other calcium-binding proteins, such as S-100 and calmodulin, which induce transformation or proliferation of glia, occur in astrocytes, it is conceivable that the expression of calbindin after ischaemia might be an important part of the process of gliosis.en_GB
dc.language.isoenen
dc.publisherLippincott, Williams & Wilkinsen_GB
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/8930964en_GB
dc.rightsArchived with thanks to Neuroreporten_GB
dc.subject.meshAnimals-
dc.subject.meshAstrocytes-
dc.subject.meshCalcium-Binding Protein, Vitamin D-Dependent-
dc.subject.meshGerbillinae-
dc.subject.meshGlial Fibrillary Acidic Protein-
dc.subject.meshHippocampus-
dc.subject.meshImmunohistochemistry-
dc.subject.meshIschemic Attack, Transient-
dc.subject.meshNerve Tissue Proteins-
dc.subject.meshPyramidal Cells-
dc.subject.meshTime Factors-
dc.titleExpression of calbindin-D28K by reactive astrocytes in gerbil hippocampus after ischaemiaen
dc.typeArticleen
dc.identifier.journalNeuroreporten_GB

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