2.50
Hdl Handle:
http://hdl.handle.net/10547/294683
Title:
Calculation of protein domain structural similarity using two-dimensional representations
Authors:
Allen, B.C.P.; Grant, Guy H.; Richards, W. Graham
Abstract:
By reducing protein structures to two-dimensional representations, it is possible to speed up the alignment of the structures and hence calculate similarity indices faster that using three-dimensional representations. Using amino acid based representations gives much better discrimination between proteins and faster calculations. Taking into account the relative similarity of the amino acids involved allowed improved accuracy at very little time cost.
Citation:
Allen, B.C.P., Grant, G.H. and Richards, W.G. (2003) 'Calculation of Protein domain structural similarity using two-dimensional representations', Journal of Chemical Information and Modeling, 43(1),pp.134-143.
Publisher:
American Chemical Society
Journal:
Journal of Chemical Information and Modeling
Issue Date:
2003
URI:
http://hdl.handle.net/10547/294683
DOI:
10.1021/ci020275t
Additional Links:
http://pubs.acs.org/cgi-bin/doilookup/?10.1021/ci020275t
Type:
Article
Language:
en
ISSN:
1549-9596
Appears in Collections:
Cell and Cryobiology Research Group

Full metadata record

DC FieldValue Language
dc.contributor.authorAllen, B.C.P.en_GB
dc.contributor.authorGrant, Guy H.en_GB
dc.contributor.authorRichards, W. Grahamen_GB
dc.date.accessioned2013-06-26T14:28:57Z-
dc.date.available2013-06-26T14:28:57Z-
dc.date.issued2003-
dc.identifier.citationAllen, B.C.P., Grant, G.H. and Richards, W.G. (2003) 'Calculation of Protein domain structural similarity using two-dimensional representations', Journal of Chemical Information and Modeling, 43(1),pp.134-143.en_GB
dc.identifier.issn1549-9596-
dc.identifier.doi10.1021/ci020275t-
dc.identifier.urihttp://hdl.handle.net/10547/294683-
dc.description.abstractBy reducing protein structures to two-dimensional representations, it is possible to speed up the alignment of the structures and hence calculate similarity indices faster that using three-dimensional representations. Using amino acid based representations gives much better discrimination between proteins and faster calculations. Taking into account the relative similarity of the amino acids involved allowed improved accuracy at very little time cost.en_GB
dc.language.isoenen
dc.publisherAmerican Chemical Societyen_GB
dc.relation.urlhttp://pubs.acs.org/cgi-bin/doilookup/?10.1021/ci020275ten_GB
dc.rightsArchived with thanks to Journal of Chemical Information and Modelingen_GB
dc.titleCalculation of protein domain structural similarity using two-dimensional representationsen
dc.typeArticleen
dc.identifier.journalJournal of Chemical Information and Modelingen_GB
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